drugset / Trial / NCT06184698

Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer

NCT06184698 ↗

Phase 2 Recruiting 173 enrolled Hebei Medical University Fourth Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a multi-center, single-arm study to investigate the efficacy and safety of liposomal irinotecan+5-FU/LV+ bevacizumab as second-line therapy in metastatic colorectal cancer in Chinese population.

Timeline

Start
2024-01-01
Primary completion
2026-02-01
Completion
2027-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 5 mg/kg —
Subject IRINOTECAN Small molecule 70 mg/m2 —
Subject LV Unknown — —
Subject fluorouracil Small molecule 2400 mg/m2 —

Indications