drugset / Trial / NCT06189508

A Study to Evaluate Single Subcutaneous Doses of NXT007 Among Injection Sites Abdomen, Upper Arm, and Thigh in Healthy Male Participants

NCT06189508

Phase 1 Completed 48 enrolled Hoffmann-La Roche
Non-randomizedParallel-groupOpen-labelBasic science

Summary

This is a Phase I, open-label, non-randomized, parallel-group, single-dose study in healthy adult male participants. The aim is to investigate the relative bioavailability (rBA) of NXT007 among subcutaneous (SC) injection sites (abdomen, upper arm, and thigh) and the absolute bioavailability (aBA) of SC NXT007 administration. In addition, the pharmacodynamic, safety, tolerability, and immunogenicity of a single dose of NXT007 following SC or intravenous (IV) administration are assessed.

Timeline

Start
2024-02-14
Primary completion
2024-12-22
Completion
2024-12-22

Drugs

EvaluationDrugModalityDoseRoute
Subject NXT007 Unknown Subcutaneous

Indications

No indication recorded.