drugset / Trial / NCT06194825

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy

NCT06194825 ↗

Phase 3 Active not recruiting 64 enrolled AstraZeneca
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to investigate the effect of eplontersen compared to placebo on the reduction of serum TTR concentration and long-term safety in Chinese participants with hereditary or wild-type transthyretin amyloid cardiomyopathy.

Timeline

Start
2023-12-01
Primary completion
2026-05-13
Completion
2027-01-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Eplontersen Antisense oligonucleotide — Subcutaneous

Indications