drugset / Trial / NCT06206291
Cannabidiol in the Treatment of Opioid Use Disorder
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The long-term goal of the project is to determine whether cannabidiol (CBD) can reduce craving and relapse in individuals with opioid use disorder (OUD). The first phase of our project was an open cross-over design study in healthy individuals to confirm the safety and pharmacokinetic (PK) effects of CBD. This next phase is to determine whether CBD can serve as a potential adjunct treatment to reduce craving and anxiety in individuals with OUD maintained on opioid agonist therapy.
Timeline
- Start
- 2023-10-04
- Primary completion
- 2024-04-04
- Completion
- 2024-04-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cannabidiol | Other / unclassified | 200 mg | — |
| Comparator | Cannabidiol | Other / unclassified | 400 mg | — |