drugset / Trial / NCT06206291

Cannabidiol in the Treatment of Opioid Use Disorder

NCT06206291

Phase 2 Completed 76 enrolled Yasmin Hurd
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The long-term goal of the project is to determine whether cannabidiol (CBD) can reduce craving and relapse in individuals with opioid use disorder (OUD). The first phase of our project was an open cross-over design study in healthy individuals to confirm the safety and pharmacokinetic (PK) effects of CBD. This next phase is to determine whether CBD can serve as a potential adjunct treatment to reduce craving and anxiety in individuals with OUD maintained on opioid agonist therapy.

Timeline

Start
2023-10-04
Primary completion
2024-04-04
Completion
2024-04-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cannabidiol Other / unclassified 200 mg
Comparator Cannabidiol Other / unclassified 400 mg