drugset / Trial / NCT06210217

Effect of TEE-guided Non-fluid Limited Combined With Dobutamine on Hepatic Venous Blood Flow Spectrum

NCT06210217

Phase 0 Unknown 51 enrolled Sichuan University
RandomizedParallel-groupDouble-blindOther

Summary

Patients meeting enrollment criteria will be randomized 1:1 to either the dobutamine or the control group. In the dobutamine group, 3\~6μg/kg/min dobutamine will be injected intravenously after anesthesia induction until hemostasis is completed. To ensure preload, transesophageal echocardiography (TEE) will be used to monitor left ventricular end-diastolic volume (LVEDV) and stroke volume (SV). In the control group, 3mL/h normal saline will be injected intravenously after anesthesia induction until hemostasis is completed, and the liquid will be restricted according to the currently commonly used principle of low central venous pressure(LCVP), nitroglycerin can be used if necessary.

Timeline

Start
2024-02-01
Primary completion
2024-03-30
Completion
2024-04-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Dobutamine Small molecule Intravenous

Indications

No indication recorded.