drugset / Trial / NCT06213428

Effects of Probiotics on Synaptic Plasticity During the Menstrual Cycle

NCT06213428 ↗

Phase 1 Unknown 40 enrolled McMaster University
RandomizedCrossoverTriple-blindBasic science

Summary

Modulation of our gut microbiota through probiotics, can improve our emotional state, decrease pain sensitivity, improve cognitive processes, increase neurotransmitter levels and alter functional connectivity. In addition, probiotics regulate estrogen levels. Estrogen levels have been recognized to influence the gut microbiota, impact neural activity, memory, and cognition. This study aims 1) to determine whether probiotics can increase the propensity for synaptic plasticity in females and 2) to determine if there are differences in the propensity for plasticity depending on the phase of the menstrual cycle.

Timeline

Start
2024-01
Primary completion
2025-05
Completion
2025-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Progressive Perfect Probiotic Other / unclassified — —

Indications

No indication recorded.