drugset / Trial / NCT06213987

The Efficacy Tretinoin Cream in the Treatment of Axillary Hyperpigmentation Associated With Acanthosis Nigricans

NCT06213987

Phase 3 Completed 20 enrolled Srinakharinwirot University
RandomizedParallel-groupTriple-blindTreatment

Summary

The goal of this randomized intra-individual design with a split-side axillary approach is to comparing the efficacy of 0.025% tretinoin cream against a cream-based formulation in the treatment of axillary hyperpigmentation associated with acanthosis nigricans. The main questions it aims to answer are: * The efficacy of 0.025% tretinoin cream and cream based in the treatment of axillary hyperpigmentation associated with acanthosis nigricans. * The safety of 0.025% tretinoin cream and cream based in the treatment of axillary hyperpigmentation associated with acanthosis nigricans. Participants were randomly assigned to apply both 0.025% tretinoin cream and the cream-based product on opposing sides of the axillary region.

Timeline

Start
2024-02-01
Primary completion
2024-06-01
Completion
2024-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Tretinoin Small molecule 0.025 % Topical