Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction

Summary

This study will evaluate the impact of colchicine on the change in coronary flow reserve (CFR), a marker for coronary microvascular dysfunction (CMD), compared to placebo in patients with heart failure and ejection fraction above 40% (including patients with improved EF).

Timeline

Start

2024-03-01

Primary completion

2025-10-01

Completion

2026-03-01

Drugs

Indications