drugset / Trial / NCT06217354

Efficacy of Carbetocin in Prevention of Postpartum Hemorrhage in Obese Versus Non Obese Women

NCT06217354

Phase 1/2 Completed 150 enrolled Cairo University
RandomizedParallel-groupOpen-labelPrevention

Summary

Postpartum hemorrhage \[PPH\] can have serious consequences and is the leading cause of maternal mortality globally. Uterine contractility plays an important role in post-delivery uterine involution; impaired contractility can contribute to PPH. Should contractility be impaired among obese women, there would be implications for management. Therefore, the investigators sought to investigate whether obese women would also experience a need for more uterine agents during the management of an obstetric hemorrhage.

Timeline

Start
2023-07-06
Primary completion
2023-10-25
Completion
2023-11-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Carbetocin Peptide 100 ug Intravenous

Indications