drugset / Trial / NCT06218550
Delta-8-THC vs. Delta-9-THC on Simulated Driving Performance
Phase 1
Completed
30 enrolled
Johns Hopkins University
Substance Abuse and Mental Health Services Administration (SAMHSA) · collab
RandomizedCrossoverDouble-blindBasic science
Summary
Delta-8-THC is an isomer of delta-9-THC that has become widely available due to the legalization of hemp and its derivatives. Very little controlled research has been conducted with delta-8-THC and some research suggests it produces similar effects to delta-9-THC, albeit at lower potency. The present study will evaluate the dose effects of delta-8-THC, compared with delta-9-THC, on simulated driving performance, field sobriety tests, cognitive performance, and biomarkers of exposure to cannabinoids. The results will inform policy and education related to impairment due to acute delta-8-THC exposure via vaporization and oral ingestion.
Timeline
- Start
- 2024-07-01
- Primary completion
- 2025-09-08
- Completion
- 2025-09-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Delta-8-Tetrahydrocannabinol | Other / unclassified | 30 mg | Oral |
| Subject | Delta-8-Tetrahydrocannabinol | Other / unclassified | 60 mg | Oral |
| Subject | Dronabinol | Other / unclassified | 30 mg | Oral |