drugset / Trial / NCT06218914

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

NCT06218914 ↗

Phase 1 Recruiting 108 enrolled AstraZeneca
Non-randomizedSequentialOpen-labelTreatment

Summary

Phase I Study, a master protocol to investigate TCR-Engineered T cells recognizing KRAS mutations in adult subjects with Unresectable, Advanced, and/or Metastatic Solid Tumors.

Timeline

Start
2024-03-22
Primary completion
2027-08-30
Completion
2043-11-18

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD0240 Cell therapy — —
Subject NT-112 Cell therapy — —