drugset / Trial / NCT06226545

A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease

NCT06226545 ↗

Phase 2 Completed 41 enrolled Lassen Therapeutics Inc.
RandomizedParallel-groupDouble-blindTreatment

Summary

LASN01 is a novel, fully human antibody directed against the human IL-11 receptor being developed for treatment of patients with thyroid eye disease (TED). The primary and secondary objectives of this study are to evaluate the treatment effect, safety, and pharmacokinetics of LASN01 administered IV in patients with TED with no prior anti-IGF-1R treatment or in patients with TED who have previously received teprotumumab treatment.

Timeline

Start
2024-03-05
Primary completion
2025-04-22
Completion
2025-04-22

Drugs

EvaluationDrugModalityDoseRoute
Subject LASN01 Monoclonal antibody — Intravenous