drugset / Trial / NCT06233903

18F-mFBG Expression in Neural Crest Tumors and Organs Innervated by the Sympathetic Nervous System

NCT06233903

NaSingle-groupOpen-labelDiagnostic

Summary

This is a prospective Phase 2 study being performed to document the relationship between 18F-mIBG positron emission tomography (PET) findings in subjects, and expression of the norepinephrine transporter. In addition to collecting safety data for the imaging agent, the study aims to: * compare the findings against other catacholamine transporters * evaluate the imaging results at different time points and in different organs * assess the quality of images with lower doses * compare the ability to detect neuroblastoma lesions against other imaging agents, and in other tumors

Timeline

Start
2025-01
Primary completion
2025-09
Completion
2025-12

Drugs

EvaluationDrugModalityDoseRoute
Subject M-FLUOROBENZYLGUANIDINE Diagnostic / imaging agent