drugset / Trial / NCT06235918

Neoadjuvant Tislelizumab Plus Chemotherapy for Resectable Locally-advanced Head and Neck Squamous Cell Carcinoma

NCT06235918 ↗

Phase 2 Unknown 30 enrolled Xiang Lu
NaSingle-groupOpen-labelTreatment

Summary

For resectable squamous cell carcinoma of the head and neck , novel therapeutic approaches are still needed to improve outcomes. Neoadjuvant immunochemotherapy is considered as a potentially effective strategy. The purpose of this study is to evaluate the safety and efficacy of neoadjuvant of tislelizumab combined with platinum doublet for resectable locally-advanced head and neck squamous-cell carcinoma .

Timeline

Start
2023-01-01
Primary completion
2025-01-01
Completion
2026-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule 5 unknown Intravenous
Subject Nab-paclitaxel Small molecule 260 mg/m2 —
Subject Tislelizumab Monoclonal antibody 200 mg Intravenous