drugset / Trial / NCT06238401

An Open-label, Multi-center, Dose-escalation and Cohort Expansion Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile and Efficacy of ACR246 in Patients With Advanced Solid Tumors

NCT06238401 ↗

Phase 1 Recruiting 77 enrolled Hangzhou Adcoris Biopharmacy Co., Ltd
NaSingle-groupOpen-labelTreatment

Summary

The goal of the study is to evaluate the safety and tolerability of ACR246 in patients with advanced solid tumors, to determine the maximum tolerated dose (MTD) and Phase II recommended dose (RP2D) of ACR246.

Timeline

Start
2024-10-29
Primary completion
2026-05-30
Completion
2026-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject ACR246 Unknown 80 mg Intravenous

Indications