drugset / Trial / NCT06239311
Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Atopic dermatitis is an ongoing condition that causes skin irritation, redness, and itchiness. Treatments are usually topical - applied to the skin (e.g., moisturisers or medicated creams) - but a wider variety of systemic treatments (that target the whole body) are needed for those whose condition does not improve with topical treatments. Methotrexate, a drug approved for similar conditions such as arthritis and psoriasis, has been shown to improve atopic dermatitis. This randomised, controlled clinical trial will investigate how effective.
Timeline
- Start
- 2024-02-27
- Primary completion
- 2026-11
- Completion
- 2027-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Methotrexate | Small molecule | 20 mg | Subcutaneous |