drugset / Trial / NCT06239311

Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.

NCT06239311

Phase 3 Recruiting 277 enrolled medac GmbH
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Atopic dermatitis is an ongoing condition that causes skin irritation, redness, and itchiness. Treatments are usually topical - applied to the skin (e.g., moisturisers or medicated creams) - but a wider variety of systemic treatments (that target the whole body) are needed for those whose condition does not improve with topical treatments. Methotrexate, a drug approved for similar conditions such as arthritis and psoriasis, has been shown to improve atopic dermatitis. This randomised, controlled clinical trial will investigate how effective.

Timeline

Start
2024-02-27
Primary completion
2026-11
Completion
2027-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Methotrexate Small molecule 20 mg Subcutaneous

Indications