drugset / Trial / NCT06241469

Efficacy and Safety of Sintilimab Combined With Nab-paclitaxel and Tegio (aTS) as First-line Treatment of Unresectable Locally Advanced, Recurrent or Metastatic Adenocarcinoma of Gastric and Gastroesophageal Junction,a Phase II Clinical Study

NCT06241469

Phase 2 Not yet recruiting 40 enrolled Wu Jun
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to find better protocal for adenocarcinoma of the gastric and gastroesophageal juncion. The main question is aim to answer is: 1\. The efficacy and safety of PD-1 monoclonal antibody (Sintilimab) combined with nab-paclitaxel and S-1 in the first-line treatment of advanced gastric and gastroesophageal junction adenocarcinoma. Participants will be given PD-1 monoclonal antibody, nab-paclitaxel and tegio.

Timeline

Start
2024-02-03
Primary completion
2026-08-02
Completion
2027-02-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Paclitaxel Small molecule
Subject Sintilimab Monoclonal antibody
Subject Tegio Unknown