An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel

Summary

The purpose of this study is to investigate the ability of an experimental dentifrice containing 1150 parts per million (ppm) fluoride to remineralize acid-softened dental enamel and help prevent further demineralization compared to a 0 ppm fluoride placebo dentifrice and a marketed, fluoride-containing dentifrice (Reference Dentifrice).

Timeline

Start

2024-02-26

Primary completion

2024-05-07

Completion

2024-05-07

Outcome

Met primary endpoint

registry analysis (superiority test); Test Dentifrice (Treatment A) vs Placebo Control Dentifrice (Treatment B); p = 0.0012 NCT06242444 ↗

Drugs

Indications