drugset / Trial / NCT06244771

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

NCT06244771 ↗

Phase 1/2 Recruiting 403 enrolled Frontier Medicines Corporation
NaSequentialOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluate FMC-376 in participants with advanced solid tumors with KRAS G12C mutations. This clinical trial will be conducted in 3 parts: Phase 1A (Dose Escalation), Phase 1B (Dose Expansion), and Phase 2 (Cohort Expansion). Multiple dose levels in participants with advanced solid tumors will be evaluated.

Timeline

Start
2024-02-12
Primary completion
2027-10
Completion
2028-04

Drugs

EvaluationDrugModalityDoseRoute
Subject FMC-376 Unknown — Oral