drugset / Trial / NCT06246149
Adjuvant Tebentafusp in High Risk Ocular Melanoma
Phase 3
Recruiting
290 enrolled
European Organisation for Research and Treatment of Cancer - EORTC
Immunocore Ltd · collabNorthwell Health · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
At least 50% of patients with high-risk primary uveal melanoma will develop a recurrence following treatment of the primary tumour. Observation is currently the standard of care in the non-metastatic setting. Tebentafusp is the first agent proven to improve overall survival in patients with metastatic uveal melanoma in a randomized trial. Based on the results in the advanced setting, it is hypothesized that treatment with tebentafusp may reduce the risk of development of disease recurrence.
Timeline
- Start
- 2024-11-11
- Primary completion
- 2032-11
- Completion
- 2032-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tebentafusp | Protein / enzyme biologic | 68 ug | Intravenous |