drugset / Trial / NCT06246851
BCG Revaccination Study in Diabetic and Non-Diabetic Adults
Non-randomizedParallel-groupOpen-labelOther
Summary
The purpose of this study is to: 1. explore whether investigators can make BCG more effective by giving it in a different way. For this, aerosol inhaled BCG will be compared against the conventional BCG injection. 2. explore if there are differences in response to re-vaccination in healthy volunteers with and without Type 2 Diabetes. It will involve 36 previously BCG-vaccinated participants. Bronchoscopies will be performed 14 days post-challenge to measure BCG recovered from bronchial samples. Blood tests will be taken to look at potential immunological markers of immunity.
Timeline
- Start
- 2024-04-03
- Primary completion
- 2028-08-31
- Completion
- 2028-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BCG Danish | Vaccine | 100000 unknown | Other |
| Subject | BCG Danish | Vaccine | 200000 unknown | Other |
| Subject | BCG Danish | Vaccine | 1e+06 unknown | Other |
| Subject | BCG Danish | Vaccine | 2e+06 unknown | Other |