drugset / Trial / NCT06252584

Multi-peptide Vaccination Adjuvanted With XS15 in Acute Myeloid Leukemia Patients

NCT06252584 ↗

Phase 1 Not yet recruiting 20 enrolled University Hospital Tuebingen
NaSingle-groupOpen-labelTreatment

Summary

The aim of this Phase I study is to evaluate the immunogenicity along with safety and toxicity as well as first efficacy of a multi-peptide vaccine adjuvanted with the TLR1/2 ligand XS15 emulsified in Montanide ISA 51 VG (AML-VAC-XS15) in AML patients who have achieved CR or CRi with first line treatment.

Timeline

Start
2024-05-02
Primary completion
2026-05-02
Completion
2026-11-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Multipeptide Vaccine AML-VAC-XS15 Vaccine — Subcutaneous