drugset / Trial / NCT06260709

A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis

NCT06260709 ↗

Phase 2 Active not recruiting 80 enrolled Novo Nordisk A/S
NaSingle-groupOpen-labelTreatment

Summary

This study will test a medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis. It will look at how safe this medicine is in the long term and if it can reduce symptoms of a heart disease due to TTR amyloidosis, such as heart failure. It is an extension to a study called "A research study to look at how a new medicine called NNC6019-0001 works and how safe it is for people who have a heart disease due to TTR amyloidosis". Only participants who have completed that study will be invited for this new study. Participants will get NNC6019-0001, regardless of whether they got placebo or NNC6019-0001 in the first study. The study will last for up to 157 weeks (36 months/3 years).

Timeline

Start
2024-02-20
Primary completion
2028-02-29
Completion
2028-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject NNC6019-0001 Monoclonal antibody — Intravenous

Indications