drugset / Trial / NCT06263244

Specifying the Anti-inflammatory Effects of Ziltivekimab

NCT06263244 ↗

Phase 3 Recruiting 40 enrolled Academic Medical Center - University of Amsterdam
RandomizedParallel-groupQuadruple-blindPrevention

Summary

The goal of this randomized, double blind, placebo controlled trial is to study whether ziltivekimab therapy reduces arterial wall inflammation as assessed by imaging, and reduces the systemic inflammatory tone as assessed by circulating monocytes, inflammatory biomarkers and proteomics.

Timeline

Start
2024-05-03
Primary completion
2026-07-01
Completion
2026-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ziltivekimab Monoclonal antibody 15 mg Subcutaneous

Indications