drugset / Trial / NCT06264440
A Study to Assess the Potential for Gastric-pH Dependent Drug-Drug Interactions of BIIB122 With a Proton Pump Inhibitor in Healthy Participants
Non-randomizedCrossoverOpen-labelTreatment
Summary
The primary objective of the study is to evaluate the effects of a proton pump inhibitor (PPI) \[rabeprazole\] on BIIB122 pharmacokinetics (PK) after a single dose in healthy participants. The secondary objective of the study is to evaluate the safety and tolerability of BIIB122, with and without a PPI (rabeprazole), after a single dose in healthy participants.
Timeline
- Start
- 2024-02-12
- Primary completion
- 2024-06-18
- Completion
- 2024-06-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BIIB122 | Small molecule | — | Oral |
| Subject | Rabeprazole | Small molecule | — | — |
Indications
No indication recorded.