drugset / Trial / NCT06270576
Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma
Non-randomizedParallel-groupOpen-labelBasic science
Summary
A phase I clinical research study aimed at determining mechanisms that regulate airway mucosal inflammation in asthma endotypes using intranasal administration of endotoxin (lipopolysaccharide from E. coli) in healthy controls and subjects diagnosed with asthma.
Timeline
- Start
- 2024-04
- Primary completion
- 2028-04
- Completion
- 2028-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lipopolysaccharide | Other / unclassified | — | Intranasal |