drugset / Trial / NCT06275763
Optimal Medical Treatment of Difficult-to-treat Hypertension
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to evaluate best medical management to achieve the BP goals of ESC/ESH (120-129 / 70-79 mmHg) in HT patients who are \<65 years old and ineffectively treated (BP ≥ 130/80 mg) with 3 or more antihypertensive drugs
Timeline
- Start
- 2023-10-20
- Primary completion
- 2025-12-01
- Completion
- 2025-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amlodipine | Other / unclassified | — | — |
| Subject | Eplerenone | Unknown | — | — |
| Subject | Indapamide | Small molecule | — | — |
| Subject | Olmesartan | Other / unclassified | — | — |
| Subject | Perindopril | Small molecule | — | — |
| Subject | Spironolactone | Small molecule | — | — |
| Subject | Torasemide | Unknown | — | — |
| Subject | hydrocholothiazide | Unknown | — | — |