drugset / Trial / NCT06277219

A First-in-Human, Phase 1/2 Study of LAT010 in Patients With Advanced Solid Tumors (LIGHTSPEED-1)

NCT06277219 ↗

Phase 1/2 Recruiting 150 enrolled Latticon Antibody Therapeutics, Inc
Non-randomizedSequentialOpen-labelTreatment

Summary

This is an open-label, multicenter, Phase 1/2, first-in-human (FIH), dose-escalation and cohort-expansion study of LAT010 to evaluate the safety, tolerability, immunogenicity, PK, PD, and antitumor activity in patients with advanced solid tumors. The study consists of 2 parts: Phase 1 dose-escalation and Phase 2 cohort expansion.

Timeline

Start
2024-06-05
Primary completion
2026-12
Completion
2027-03

Drugs

EvaluationDrugModalityDoseRoute
Subject LAT010 Protein / enzyme biologic — Intravenous

Indications