A Clinical Study of AL2846 Capsule Combined With Gemzar Injection in the Treatment of Advanced Pancreatic Cancer

Summary

This is a clinical study to observe the tolerance and primary efficacy of AL2846 capsules combined with Gemzar injection in patients with pancreatic cancer, and to determine the recommended dosage and administration method for subsequent clinical studies.

Timeline

Start

2018-08-23

Primary completion

2021-10-25

Completion

2023-05-01

Publications

• Liu R, Ji Z, Wang X, Xin J, Zhu L, Ge S, Zhang L, Bai M, Ning T, Yang Y, Li H, Deng T, Ba Y. Efficacy and safety of multi-target tyrosine kinase inhibitor AL2846 combined with gemcitabine in pancreatic cancer. Invest New Drugs. 2025 Feb;43(1):81-92. doi: 10.1007/s10637-024-01485-5. Epub 2025 Jan 6.

Drugs

Indications