Postoperative Intraperitoneal Pain Management Following Laparoscopic Cholecystectomy

Phase 3 Completed 46 enrolled Future University in Egypt

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Postoperative pain management is essential and the inability to treat acute pain appropriately in the first 48 postoperative hours represents a risk factor for developing chronic pain. No. study has investigated IP granisetron as an adjuvant to standard care for postoperative pain management in patients undergoing LC.

Timeline

Start: 2024-02-29
Primary completion: 2024-12-04
Completion: 2024-12-04

Publications

Bayoumi HM, Abdelaziz DH, Boraii S, Bendas ER, El Said NO. Intraperitoneal Granisetron for Post-Laparoscopic Cholecystectomy Pain Management: A Double-Blinded, Randomized Controlled Trial. Pharmacotherapy. 2025 Sep;45(9):547-556. doi: 10.1002/phar.70046. Epub 2025 Jul 23.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Granisetron	Other / unclassified	2 ml	Other

Indications

No indication recorded.