Effectiveness and Tolerability of Influenza Vaccine in Patients at Risk for Severe and Complicated Influenza

Summary

The aim of the study is to evaluate simultaneously the immunological and clinical efficacy and tolerability of an influenza vaccine, inactivated, quadrivalent, with cleaved virus, in patients at risk for severe and complicated influenza routinely vaccinated against influenza in family medicine clinics or specialty clinics (pediatric, internal medicine, cardiology, gynecological diabetes, pregnant women, transplant).

Timeline

Start

2020-09-15

Primary completion

2023-08-23

Completion

2026-05-01

Publications

• Zasztowt-Sternicka M, Jagielska A, Rzad M, Szymusik I, Hallmann E, Brydak L, Nitsch-Osuch A. Immunogenicity of inactivated quadrivalent influenza vaccine in pregnant women, including the level of postvaccination antibodies in umbilical cord blood. Vaccine. 2025 Apr 19;53:127047. doi: 10.1016/j.vaccine.2025.127047. Epub 2025 Apr 8.

Drugs

Indications