drugset / Trial / NCT06292650

Safety and Efficacy Study of Novel Gene Therapy ZM-02 for Retinitis Pigmentosa Patients

NCT06292650 ↗

Phase 0 Recruiting 12 enrolled Zhongmou Therapeutics
RandomizedParallel-groupDouble-blindTreatment

Summary

This is zM-02's safety, tOlerability, and efficacy in retinitis pigmentOsa first-in-humaN study (MOON). This trial is meant to evaluate the safety and efficacy of ZM-02 in Retinitis pigmentosa (RP) patients. Unilateral intravitreal injections (IVT) will be given into the subject's Study Eye.

Timeline

Start
2024-02-25
Primary completion
2027-12-25
Completion
2028-12-25

Drugs

EvaluationDrugModalityDoseRoute
Subject ZM-02 Gene therapy (AAV / viral vector) — Intravitreal

Indications