drugset / Trial / NCT06294821

4AP for Carpal Tunnel Syndrome (CTS)

NCT06294821

Phase 2 Not yet recruiting 160 enrolled John Elfar
RandomizedParallel-groupTriple-blindTreatment

Summary

The investigators have found recent promising data supporting the use of a currently FDA approved drug, 4-aminopyridine, in the treatment of nerve injury including compression neuropathy. The purpose of this research is determine whether 4-aminopyridine can treat carpal tunnel syndrome or delay the need for formal surgical release in patients with known carpal tunnel syndrome who would otherwise undergo surgery.

Timeline

Start
2026-11
Primary completion
2027-12
Completion
2028-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dalfampridine Small molecule 10 mg