drugset / Trial / NCT06303713

LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancer

NCT06303713

Phase 1 Active not recruiting 37 enrolled Dana-Farber Cancer Institute Novartis · collab
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to see whether the combination of a chemotherapy drug, carboplatin, along with the radioligand treatment, 177Lu-PSMA-617, is safe in treating prostate cancer and whether the combination is effective in shrinking or preventing growth of prostate cancer. The names of the study drugs used in this research study are: * Carboplatin (A type of chemotherapy) * 177Lu-PSMA-617 (A type of radioligand therapy)

Timeline

Start
2024-05-22
Primary completion
2026-10-19
Completion
2027-03-19

Drugs

EvaluationDrugModalityDoseRoute
Subject 177Lu-PSMA-617 Other / unclassified Intravenous
Subject Carboplatin Small molecule Intravenous