drugset / Trial / NCT06304636

Descartes-15 for Patients With Relapsed/Refractory Multiple Myeloma

NCT06304636 ↗

Phase 1 Terminated 4 enrolled Cartesian Therapeutics
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a Phase I dose-escalation study to evaluate the safety, tolerability and preliminary efficacy of an autologous BCMA-targeting RNA-engineered CAR T-cell therapy in patients with Relapsed/Refractory Multiple Myeloma. The cell product is referred to as Descartes-15

Timeline

Start
2024-06-19
Primary completion
2025-04-14
Completion
2025-11-13

Outcome

Outcome not reported

Stopped (Enrollment): “Phase 1 enrollment completed. Further clinical development terminated”

Drugs

EvaluationDrugModalityDoseRoute
Subject Descartes-15 Cell therapy — —

Indications