drugset / Trial / NCT06304636
Descartes-15 for Patients With Relapsed/Refractory Multiple Myeloma
Non-randomizedSequentialOpen-labelTreatment
Summary
This is a Phase I dose-escalation study to evaluate the safety, tolerability and preliminary efficacy of an autologous BCMA-targeting RNA-engineered CAR T-cell therapy in patients with Relapsed/Refractory Multiple Myeloma. The cell product is referred to as Descartes-15
Timeline
- Start
- 2024-06-19
- Primary completion
- 2025-04-14
- Completion
- 2025-11-13
Outcome
Outcome not reported
Stopped (Enrollment): “Phase 1 enrollment completed. Further clinical development terminated”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Descartes-15 | Cell therapy | — | — |