drugset / Trial / NCT06308445

Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis

NCT06308445

Phase 2 Not yet recruiting 25 enrolled University Hospital, Toulouse
NaSingle-groupOpen-labelTreatment

Summary

The hypothesize of this research is that rapamycin is effective and well-tolerated in teenagers with familial adenomatous polyposis (FAP). Rapamycin could be effective in blocking the formation of adenomas and/or their evolution by decreasing their size and number. Researchers aim to assess the safety profile of rapamycin in FAP adolescents using a 2 low dose regimen.

Timeline

Start
2026-09-01
Primary completion
2030-09
Completion
2030-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Sirolimus Small molecule