drugset / Trial / NCT06311513
Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction
Phase 4
Recruiting
40 enrolled
Hospital for Special Surgery, New York
Arthritis Foundation · collabEmory University · collab
RandomizedParallel-groupSingle-blindPrevention
Summary
The goal of this pilot randomized clinical trial is to look into the efficacy of concentrated bone marrow aspirate (cBMA) in improving post traumatic osteoarthritis (PTOA) symptoms in patients undergoing revision anterior cruciate ligament reconstruction surgery. The main questions it aims to answer are whether clinical outcomes, such as pain, are improved in patients who get cBMA with surgery, if there is a change in circulating markers of inflammation and what part of the cellular and molecular composition of cBMA may explain its effects.
Timeline
- Start
- 2024-01-22
- Primary completion
- 2027-12
- Completion
- 2028-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Concentrated Bone Marrow Aspirate Injection | Cell therapy | — | Other |