drugset / Trial / NCT06315699

Clemastine Fumarate in the Treatment of Neurodevelopmental Delays in Williams Syndrome

NCT06315699

Phase 2 Completed 28 enrolled Qilu Hospital of Shandong University
RandomizedCrossoverTriple-blindTreatment

Summary

This study focuses on therapeutic targets for cognitive, motor, and social impairments in Williams syndrome by reversing brain myelin defects caused by GTF2I. The primary objective of the study was to test and evaluate the initial efficacy and safety of Clomastine fumarate in the treatment of Williams syndrome.

Timeline

Start
2024-03-20
Primary completion
2025-03-02
Completion
2025-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Clemastine Small molecule 0.178 mg/kg