drugset / Trial / NCT06320041
Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery
Phase 4
Recruiting
162 enrolled
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The goal of this clinical trial\] is to further explore the effectiveness and safety of oxelidine in the treatment of moderate to severe acute pain after orthopedic surgery. The main question it aims to answer is: Pain management after orthopaedic surgery provides more effective and safe drug options, provides new options for clinical treatment, and provides a scientific basis for clinical practice. Participants will be asked to pain score in the different time, treatments they'll be given and use optimal drug. Researchers will compare analgesic effect of oxelidine of different dose.
Timeline
- Start
- 2024-08-01
- Primary completion
- 2026-12-31
- Completion
- 2026-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hydromorphone | Other / unclassified | 0.3 mg | — |
| Subject | Oliceridine | Other / unclassified | 0.35 mg | — |
| Subject | Oliceridine | Other / unclassified | 0.5 mg | — |
Indications
No indication recorded.