drugset / Trial / NCT06326411

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

NCT06326411 ↗

Phase 1 Recruiting 230 enrolled Nested Therapeutics, Inc
NaSequentialOpen-labelTreatment

Summary

This is a two-part Phase 1, open label, multi-center, single arm, non-randomized, multiple dose, safety, pharmacokinetic (PK) and preliminary efficacy study of single agent NST-628 in adult patients with MAPK pathway mutated/dependent advanced solid tumors who have exhausted standard treatment options.

Timeline

Start
2024-04-09
Primary completion
2028-11
Completion
2029-11

Drugs

EvaluationDrugModalityDoseRoute
Subject NST-628 Small molecule — Oral