drugset / Trial / NCT06331702

Immunogenicity of Japanese Encephalitis Vaccine Co-administered With Measles-Mumps-Rubella Vaccine (MMR)

NCT06331702

Phase 4 Completed 408 enrolled Liaoning Chengda Biotechnology CO., LTD
RandomizedParallel-groupOpen-labelPrevention

Summary

This is a phase IV, randomized, controlled, open-label study proceed in healthy children aged 8 months in China. The primary objective is to demonstrate the immunogenicity of simultaneous administration of JEV-I and MMR is not inferior to that of separate administration, as measured by seroconversion rates and antibody titers against the four antigens. The secondary objective is to describe the safety of the vaccines when administered simultaneously or separately.

Timeline

Start
2024-03-02
Primary completion
2025-02-11
Completion
2025-02-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Measles-Mumps-Rubella Vaccine Vaccine 0.5 ml Subcutaneous
Subject Vero cell-drived inactive Japanese encephalitis vaccine Vaccine 0.5 ml Intramuscular