drugset / Trial / NCT06341621

Chemotherapy Omission in ER+/HER2- Breast Cancer With 1-3 Positive Lymph Nodes Receiving Extended Adjuvant Abemaciclib

NCT06341621

Phase 3 Recruiting 1900 enrolled Fudan University
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective, randomized, open-label, multicenter phase III study to explore chemotherapy omission in ER+/HER2-endocrine-sensitive breast cancer with 1-3 positive lymph nodes receiving extended (3 year) adjuvant abemaciclib

Timeline

Start
2024-04-02
Primary completion
2027-02-25
Completion
2029-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Abemaciclib Small molecule 100 mg

Indications