drugset / Trial / NCT06347133
Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with hypertriglyceridemia (HTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo and be evaluated for efficacy and safety.
Timeline
- Start
- 2024-05-21
- Primary completion
- 2026-06-01
- Completion
- 2026-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Plozasiran | Small interfering RNA (siRNA) | — | Subcutaneous |