drugset / Trial / NCT06348290
Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is an open-label, non-randomized, clinical study to evaluate the drug interaction between itraconazole, rifampin or Cocktail and JMKX001899 in healthy subjects. A total of three cohorts of 72 healthy subjects were planned to be enrolled in each cohort.
Timeline
- Start
- 2024-04-01
- Primary completion
- 2024-05-31
- Completion
- 2024-09-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dextromethorphan | Unknown | — | Oral |
| Subject | Digoxin | Other / unclassified | — | Oral |
| Subject | Itraconazole | Small molecule | — | Oral |
| Subject | JMKX001899 | Unknown | — | Oral |
| Subject | Midazolam | Small molecule | — | Oral |
| Subject | Rifampicin | Small molecule | — | Oral |
| Subject | Rosuvastatin | Small molecule | — | Oral |