drugset / Trial / NCT06348927

Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR-Sensitive Mutations Combined With Co-Mutations Advanced NSCLC

NCT06348927

Phase 2 Recruiting 52 enrolled Hunan Province Tumor Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a phase II, open-label, single-arm, single-center clinical study to evaluate the preliminary efficacy of sunvozertinib in combination with anlotinib in patients with EGFR-sensitive mutations and co-mutations in locally advanced or metastatic treatment-naive non-small cell lung cancer. Condition or disease Intervention/treatment Phase Non-Small Cell Lung Cancer Drug: sunvozertinib Drug: anlotinib Phase 2

Timeline

Start
2024-07-01
Primary completion
2025-10-31
Completion
2027-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Catequentinib Small molecule 8 mg
Subject Sunvozertinib Small molecule 300 mg