drugset / Trial / NCT06350110

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)

NCT06350110 ↗

Phase 1/2 Recruiting 75 enrolled Essen Biotech
NaSingle-groupOpen-labelTreatment

Summary

This study is a preliminary investigation, with a single-group design, not randomized and transparent, focusing on treatment. Its purpose is to identify the highest dose of BH002 injection (CD19-BCMA CAR-T cells) that patients suffering from resistant systemic lupus erythematosus can tolerate.

Timeline

Start
2024-07-10
Primary completion
2025-12-10
Completion
2025-12-28

Drugs

EvaluationDrugModalityDoseRoute
Subject CD19-BCMA CAR-T cells Cell therapy — Intravenous