drugset / Trial / NCT06355180
Esketamine vs ECT for Acute Suicidality
Completed
340 enrolled
Capital Medical University
Beijing Chaoyang District Third Hospital · collabBeijing Daxing District Xinkang Hospital · collabInner Mongolia Autonomous Region Mental Health Center · collabThe Second People's Hospital of Dali Bai Autonomous Prefecture · collabWuhu Fourth People's Hospital · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
This study is a multicenter, randomized, non-inferiority, parallel-group clinical trial designed to evaluate the efficacy and safety of esketamine compared with electroconvulsive therapy (ECT) in the treatment of suicidal ideation during depressive episodes in patients with mood disorders. Furthermore, it aims to investigate the potential mechanisms underlying the anti-suicidal effects of esketamine.
Timeline
- Start
- 2024-04-16
- Primary completion
- 2025-06-13
- Completion
- 2025-08-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esketamine | Other / unclassified | 0.2 mg/kg | Intravenous |