drugset / Trial / NCT06360458

Methylprednisolone Adjunctive to Endovascular Thrombectomy for Stroke

NCT06360458

Phase 3 Active not recruiting 928 enrolled Wan-Jin Chen
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The efficacy and safety of methylprednisolone in acute ischemic stroke patients with large infarct cores (ASPECTS score \< 6 or infarct volume ≥50 mL) due to anterior circulation large vessel occlusion have not been clearly established. This is a multi-center, randomized, double-blind, placebo-controlled trial to investigate early combination therapy with methylprednisolone for reperfusion in acute large core infarction.

Timeline

Start
2024-08-01
Primary completion
2025-09-30
Completion
2030-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylprednisolone Other / unclassified 2 mg/kg Intravenous

Indications