drugset / Trial / NCT06360458
Methylprednisolone Adjunctive to Endovascular Thrombectomy for Stroke
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The efficacy and safety of methylprednisolone in acute ischemic stroke patients with large infarct cores (ASPECTS score \< 6 or infarct volume ≥50 mL) due to anterior circulation large vessel occlusion have not been clearly established. This is a multi-center, randomized, double-blind, placebo-controlled trial to investigate early combination therapy with methylprednisolone for reperfusion in acute large core infarction.
Timeline
- Start
- 2024-08-01
- Primary completion
- 2025-09-30
- Completion
- 2030-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylprednisolone | Other / unclassified | 2 mg/kg | Intravenous |