drugset / Trial / NCT06365437

A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation

NCT06365437

Phase 2 Terminated 33 enrolled ITB-Med LLC
RandomizedSequentialOpen-labelBasic science

Summary

The purpose of this study is to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of escalating doses of TCD601 when compared to rATG in de novo renal transplant patients.

Timeline

Start
2021-06-06
Primary completion
2024-12-11
Completion
2024-12-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator ATG Protein / enzyme biologic 1.5 mg/kg
Subject Siplizumab Monoclonal antibody 0.2 mg/kg
Subject Siplizumab Monoclonal antibody 0.6 mg/kg
Subject Siplizumab Monoclonal antibody 1.7 mg/kg
Subject Siplizumab Monoclonal antibody 5 mg/kg
Background Mycophenolate Mofetil Small molecule
Background Tacrolimus Small molecule

Indications

No indication recorded.