drugset / Trial / NCT06366945

Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCC

NCT06366945 ↗

Phase 2 Not yet recruiting 85 enrolled Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
NaSingle-groupOpen-labelTreatment

Summary

To explore the efficiency and safety of Tislelizumab combinated with carboplatin and polymeric micellar paclitaxel as a new neoadjuvant treatment regimen for resectable HNSCC patients with clinical positive lymph node metastasis

Timeline

Start
2024-04-20
Primary completion
2026-12-30
Completion
2029-05-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule — —
Subject Polymeric Micellar Paclitaxel Unknown 300 mg/m2 —
Subject Tislelizumab Monoclonal antibody 200 mg —